Why it matters:
Some people with NAFLD will have progressive abnormalities in the liver that can lead to liver failure
- NASH (non-alcoholic steatohepatitis). NAFLD with inflammation in the liver
- NASH with fibrosis. NAFLD with inflammation and scarring.
- Cirrhosis. NAFLD with inflammation, scarring, and permanent destruction of liver tissue
NAFLD/NASH is one of the most common causes of liver failure requiring liver transplant. Additionally, people with NAFLD are at a higher risk for cardiovascular disease and multiple types of cancer.
What you can do if you have NAFLD:
- Eat healthy food and lose weight if overweight
- Get regular exercise
- Avoid or limit alchohol
- Avoid medications that might harm the liver
- Talk with your provider about your risk for more advanced liver disease, in which case medications (pioglitazone, semaglutide) or referral to a liver specialist might be recommended
Maintaining a healthy lifestyle and body weight are the best approaches to avoiding NAFLD in the first place. We only get one liver. It's important to take care of it.
UpToDate information about NASH
Have a great week,
Dr. Topher Fox
P.S. If you missed any previous emails, the content is posted weekly here
P.P.S. Below are the pictures from my exam room wall which we are exploring for this email series.