Adiposity-based chronic disease (ABCD) arises from obesity, and represents a complex, chronic illness with multiple causitive factors - genetics and epigenetics, dietary choices, activity level, medications, sleep quality, etc.
Conditions associated with ABCD include high blood pressure, abnormal cholesterol/lipid levels, heart disease and stroke, sleep apnea, non-alcholic fatty liver disease (NAFLD), type 2 diabetes and prediabetes, and arthritis.
Why it matters:
There is a tendency in our culture to "blame the victim" of ABCD, believing ABCD is the result purely of weak will and poor choices. However, studies show while that losing weight can be difficult, sustaining weight loss is even more problematic.
- The graph below shows weight loss in response to 68 weeks of semaglutide (Ozempic/Wegovy), followed by the weight response after the medication is stopped.